TabletsMRP Under Process
Official PMBI MRP is being updated for catalog code 2701.
Locate Jan Aushadhi KendraClinical Overview
Lurasidone Hydrochloride is a benzoisothiazole second-generation atypical antipsychotic. It acts as an antagonist at dopamine D2 and 5-HT2A receptors, with potent partial agonism at 5-HT1A and high antagonism at 5-HT7 receptors, while lacking anticholinergic and H1 antihistaminic properties, offering an exceptionally clean metabolic profile with minimal weight gain or sedation. Indicated for schizophrenia and depressive episodes associated with bipolar I disorder (bipolar depression).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally once daily strictly with food (a meal containing at least 350 calories), which increases systemic absorption threefold. Swallow whole with water. Take consistently at the same time each day.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Somnolence, akathisia, nausea, parkinsonism, insomnia, restlessness. Rare/Severe: Boxed warning: Mortality in dementia patients and suicidality in young patients; neuroleptic malignant syndrome, tardive dyskinesia, and hyperprolactinemia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Boxed warnings for dementia psychosis mortality and antidepressant suicidality. Must be taken with a substantial meal (>=350 calories) to ensure therapeutic bioavailability. Contraindicated with strong CYP3A4 inhibitors (ketoconazole, clarithromycin) and strong inducers (rifampicin, carbamazepine, St. John's wort).
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Lurasidone Hydrochloride Tablets 40 mg
Lurasidone Hydrochloride is a benzoisothiazole second-generation atypical antipsychotic. It acts as an antagonist at dopamine D2 and 5-HT2A receptors, with potent partial agonism at 5-HT1A and high antagonism at 5-HT7 receptors, while lacking anticholinergic and H1 antihistaminic properties, offering an exceptionally clean metabolic profile with minimal weight gain or sedation. Indicated for schizophrenia and depressive episodes associated with bipolar I disorder (bipolar depression).
Lurasidone Hydrochloride Tablets 80 mg
Lurasidone Hydrochloride is a benzoisothiazole second-generation atypical antipsychotic. It acts as an antagonist at dopamine D2 and 5-HT2A receptors, with potent partial agonism at 5-HT1A and high antagonism at 5-HT7 receptors, while lacking anticholinergic and H1 antihistaminic properties, offering an exceptionally clean metabolic profile with minimal weight gain or sedation. Indicated for schizophrenia and depressive episodes associated with bipolar I disorder (bipolar depression).