SolutionMRP Under Process
Official PMBI MRP is being updated for catalog code 2651.
Locate Jan Aushadhi KendraClinical Overview
Triclofos Sodium is an orally administered phosphate prodrug of trichloroethanol, the active metabolite of chloral hydrate. It is rapidly hydrolyzed in the intestine and liver to trichloroethanol, which enhances inhibitory GABAergic transmission in the central nervous system, producing rapid, naturalistic sedation without significant respiratory or cardiovascular depression. Indicated for short-term pediatric sedation prior to non-invasive diagnostic procedures (EEG, MRI, CT scans, echocardiograms) and short-term insomnia.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Administer orally 30 to 45 minutes prior to the scheduled diagnostic investigation or procedure, using a calibrated oral syringe or measuring cup. Can be given with water or milk. Monitor the child continuously until fully awake.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Drowsiness, dizziness, lightheadedness, mild ataxia, nausea, vomiting, headache. Rare/Severe: Paradoxical excitement, airway obstruction during deep sedation, severe hypersensitivity, and cardiac arrhythmias at high doses.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Always monitor oxygen saturation, heart rate, and airway patency in children during procedure-related sedation. Contraindicated in severe hepatic or renal impairment and porphyria. For short-term procedure use only.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.