SprayMRP Under Process
Official PMBI MRP is being updated for catalog code 2329.
Locate Jan Aushadhi KendraClinical Overview
Midazolam Nasal Spray is an emergency rescue formulation for acute repetitive seizures and status epilepticus. Delivered across the nasal mucosa, it provides rapid systemic absorption directly into cerebral circulation via the olfactory/trigeminal pathway, bypassing hepatic first-pass metabolism to arrest prolonged convulsions within minutes. Indicated for acute treatment of intermittent, stereotypic episodes of frequent seizure activity in patients with epilepsy.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
For emergency intranasal administration only. Administer a single spray into one nostril during or immediately following a seizure cluster. If the seizure does not stop within 10 minutes, a second dose may be given in the opposite nostril if prescribed by the specialist. Call emergency medical services immediately.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nasal discomfort, throat irritation, headache, somnolence, lacrimation. Rare/Severe: Severe respiratory depression, hypoventilation, airway obstruction, and cardiac arrest.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Respiratory depression; emergency personnel or caregiver must monitor respiration and airway patency continuously. Contraindicated in acute narrow-angle glaucoma.
Schedule H1 (Prescription Required - Controlled Hospital/Rescue Use)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
