Clinical Overview
Alpha-Ketoanalogue and Essential Amino Acids is an oral nutritional therapy for chronic kidney disease (CKD). It provides keto-analogues of essential amino acids that undergo transamination in the body, taking up amino groups from circulating urea nitrogen and converting into essential amino acids without generating new urea nitrogen, reducing uremic toxins and slowing the decline of GFR in pre-dialysis renal disease. Indicated for prevention and therapy of damages due to faulty or deficient protein metabolism in chronic kidney disease in connection with limited dietary protein intake (<= 40 g/day).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Swallow whole with water during meals (divided 3 times daily). Concomitant dietary protein intake must be restricted to 0.6-0.8 g/kg/day under clinical dietetic guidance.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Mild hypercalcemia, gastrointestinal discomfort. Rare/Severe: Severe hypercalcemia.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in hypercalcemia and disturbed amino acid metabolism. Regularly monitor serum calcium and phosphate levels. Reduce intake of vitamin D if hypercalcemia develops.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered endocrinologist, diabetologist, or qualified physician before initiating, adjusting dosages of, or substituting any antidiabetic or hormonal medication.