Clinical Overview
Prednisolone Acetate / Sodium Phosphate (1% w/v eye drops) is the gold-standard topical ophthalmic corticosteroid on the WHO Model List of Essential Medicines. It delivers high corneal and intraocular penetration, suppressing cellular infiltration, capillary dilatation, fibroblast proliferation, and collagen deposition in the anterior segment. Indicated for steroid-responsive ocular inflammation (anterior uveitis, post-operative cataract inflammation, severe allergic blepharoconjunctivitis, and corneal graft rejection prophylaxis).
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Shake suspension vigorously before use. Instill one drop into the conjunctival sac 2 to 4 times daily, or hourly in severe acute uveitis during the first 24-48 hours. Taper gradually over weeks under ophthalmologist guidance. Never stop abruptly.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Transient stinging, burning, blurred vision. Rare/Severe: Steroid-induced ocular hypertension/glaucoma, posterior subcapsular cataract, secondary bacterial/fungal infections, and corneal thinning/perforation.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Contraindicated in epithelial herpes simplex keratitis (dendritic keratitis) and fungal keratitis. Periodic intraocular pressure measurement is mandatory. Always taper dosage to prevent rebound inflammation.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or ophthalmic treatment recommendations. Always consult a registered ophthalmologist or ENT specialist before initiating, changing, or instilling any ophthalmic or otic medication.