CapsulesClinical Overview
Chloramphenicol is a broad-spectrum bacteriostatic antibiotic produced by Streptomyces venezuelae. It reversibly binds to the 50S subunit of the 70S bacterial ribosome, inhibiting peptidyl transferase and peptide bond formation. Penetrates CSF, eye, and tissues exceptionally well. Because of serious toxicity risks, systemic use is strictly restricted to life-threatening infections where safer alternatives are ineffective or contraindicated, including bacterial meningitis and severe typhoid fever.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
Take orally on an empty stomach with a full glass of water, 1 hour before or 2 hours after meals. Strictly adhere to prescribed hospital dosages. Regular blood counts must be conducted during therapy.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Nausea, vomiting, diarrhea, glossitis, headache, depression. Rare/Severe: Black box warning: Irreversible aplastic anemia (fatal bone marrow aplasia occurring idiosyncratically), reversible dose-related bone marrow suppression, Gray Baby Syndrome in neonates (cardiovascular collapse, cyanosis, ashen gray color), and optic neuritis.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black box warning: Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, granulocytopenia). Systemic use must be restricted to severe infections with clear microbiological justification. Absolute contraindication in neonates and during pregnancy/lactation. Regular hematologic monitoring is mandatory.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Clinical Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice, clinical diagnosis, or treatment recommendations. Always consult a registered medical practitioner or qualified pharmacist before initiating, modifying, or substituting any medication regimen.
Polymyxin B Sulphate 5000IU + Chloramphenicol 4mg + Dexamethasone 1mg Eye/Ear Drops
Ceruminolytic Ear Drop formulation combining Paradichlorobenzene (2%), Chlorbutol (5%), Turpentine Oil (15%), and Lidocaine (2%). Paradichlorobenzene hydrates and dissolves hard impacted cerumen; turpentine oil acts as a counter-irritant and cerumen liquefier; chlorbutol provides mild antibacterial and antifungal preservation; and lidocaine relieves localized ear canal pain and tension. Indicated for softening, loosening, and removal of hardened, impacted ear wax.
Chloramphenicol Eye Ointment 1%w/w
Chloramphenicol Eye Ointment 1%w/w is an evidence-based ophthalmic/otic formulation. It acts by delivering targeted active therapeutic substances to external ocular or auditory tissues to control infection, relieve inflammation, or restore tissue homeostasis.
Chloramphenicol Capsules 500 mg
Chloramphenicol is a broad-spectrum bacteriostatic antibiotic produced by Streptomyces venezuelae. It reversibly binds to the 50S subunit of the 70S bacterial ribosome, inhibiting peptidyl transferase and peptide bond formation. Penetrates CSF, eye, and tissues exceptionally well. Because of serious toxicity risks, systemic use is strictly restricted to life-threatening infections where safer alternatives are ineffective or contraindicated, including bacterial meningitis and severe typhoid fever.
Chloramphenicol 0.5% w/v + Dexamethasone 0.1% w/v Eye/Ear Drops
Ceruminolytic Ear Drop formulation combining Paradichlorobenzene (2%), Chlorbutol (5%), Turpentine Oil (15%), and Lidocaine (2%). Paradichlorobenzene hydrates and dissolves hard impacted cerumen; turpentine oil acts as a counter-irritant and cerumen liquefier; chlorbutol provides mild antibacterial and antifungal preservation; and lidocaine relieves localized ear canal pain and tension. Indicated for softening, loosening, and removal of hardened, impacted ear wax.