Clinical Overview
Nandrolone Decanoate Injection IP (25 mg/ml, 50 mg/ml) is a synthetic 19-nortestosterone anabolic-androgenic steroid in an oily depot solution on the WHO Model List of Essential Medicines. It promotes cellular nitrogen retention, stimulates protein synthesis, stimulates renal erythropoietin secretion (enhancing erythropoiesis), and stimulates osteoblastic bone matrix synthesis. Indicated for the adjunctive management of postmenopausal and senile osteoporosis, refractory anemia associated with chronic renal failure, and severe catabolic states / muscle-wasting diseases following extensive trauma or chronic debilitating illness.
Active Pharmaceutical Ingredients
Verified Clinical References
Usage Guidelines
For Deep Intramuscular (IM) injection ONLY: 25 mg to 50 mg deep IM into the gluteal muscle once every 2 to 3 weeks (osteoporosis) or 50 mg to 100 mg weekly (renal anemia), administered strictly by a healthcare professional. Warm ampoule between hands prior to aspiration; inject slowly with a 21G needle. Maximum therapeutic cycle typically 12 weeks followed by rest.
General Administration Advice: Adhere strictly to the prescribed dosage, frequency, and treatment course. For oral medications, swallow with sufficient water. Never stop antibiotics, psychiatric medications, or antihypertensives abruptly without clinical direction.
Possible Side Effects
Common: Virilization in females (hirsutism, voice deepening, clitoromegaly, menstrual irregularities, male-pattern alopecia), acne, fluid retention, edema, and nausea. Rare/Severe: Hepatic adenomas, peliosis hepatis, severe cholestatic jaundice, dyslipidemia (decreased HDL, increased LDL), and premature epiphyseal closure in adolescents.
*Note: Individual physiological responses vary. While many patients experience few or no side effects, notify your treating physician if adverse reactions persist or if hypersensitivity (angioedema, skin rash, dyspnea) occurs.
Precautions & Warnings
Black Box Warning: Severe virilization in women which may be irreversible; hepatic toxicity and cardiovascular risk. Contraindicated in pregnant or nursing women, carcinoma of the breast or prostate, severe hepatic impairment, nephrotic syndrome, and hypercalcemia. High risk of non-medical athletic doping abuse.
Schedule H (Prescription Required)
This medication is scheduled under statutory drug regulatory frameworks (CDSCO / Drugs & Cosmetics Rules). Dispensing requires a valid medical prescription from a registered medical practitioner. Self-medication or unsupervised dosage adjustment carries significant clinical risks.
Medical Disclaimer: Statutory Gynecological, Obstetric & Endocrinological Disclaimer: The information provided is for educational and price-transparency purposes only and does not constitute medical advice or reproductive healthcare guidance. Hormonal medications, uterotonics, corticosteroids, fertility therapies, and emergency contraceptives have profound systemic actions and must be administered strictly under the supervision of a registered gynecologist, obstetrician, or endocrinologist.