Trimethoprim
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Antibiotics & Anti-Infectives treatment.
🧴 Clinical Application
Shake oral suspension well before use. Administer with measuring device. Can be taken with meals or on an empty stomach. Ensure the child drinks plenty of fluids throughout the day.
⚠️ Side Effects
Common: Nausea, vomiting, anorexia, skin rash, pruritus, mild diarrhea. Rare/Severe: Severe sulfonamide cutaneous adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), hyperkalemia, megaloblastic anemia/thrombocytopenia, crystalluria, and aseptic meningitis.
🛡️ Safety Warnings
Contraindicated in patients with known sulfonamide or trimethoprim allergy, megaloblastic anemia due to folate deficiency, severe renal impairment (CrCl < 15 mL/min), severe liver disease, and in infants under 6 weeks of age (risk of kernicterus). Monitor serum potassium and CBC in prolonged therapy.
Jan Aushadhi Products containing Trimethoprim
Found 3 generic formulation(s) containing this active ingredient.
Co-trimoxazole (Sulphamethoxazole 200mg + Trimethoprim 40mg per 5ml) Oral Suspension
Co-trimoxazole is a fixed-ratio (5:1) synergistic antibacterial combination of Sulphamethoxazole (SMX) and Trimethoprim (TMP). SMX competitively inhibits bacterial dihydropteroate synthase, while TMP inhibits dihydrofolate reductase, sequentially blocking two consecutive steps in bacterial tetrahydrofolate synthesis. Indicated for urinary tract infections, acute otitis media, Shigella enteritis, Pneumocystis jirovecii pneumonia (PJP) treatment and prophylaxis, and community-acquired MRSA skin infections.
Co-trimoxazole (Sulphamethoxazole 800mg + Trimethoprim 160mg) Tablets
Co-trimoxazole is a fixed-ratio (5:1) synergistic antibacterial combination of Sulphamethoxazole (SMX) and Trimethoprim (TMP). SMX competitively inhibits bacterial dihydropteroate synthase, while TMP inhibits dihydrofolate reductase, sequentially blocking two consecutive steps in bacterial tetrahydrofolate synthesis. Indicated for urinary tract infections, acute otitis media, Shigella enteritis, Pneumocystis jirovecii pneumonia (PJP) treatment and prophylaxis, and community-acquired MRSA skin infections.
Co-trimoxazole (Sulphamethoxazole 100mg + Trimethoprim 20mg) Tablets
Co-trimoxazole is a fixed-ratio (5:1) synergistic antibacterial combination of Sulphamethoxazole (SMX) and Trimethoprim (TMP). SMX competitively inhibits bacterial dihydropteroate synthase, while TMP inhibits dihydrofolate reductase, sequentially blocking two consecutive steps in bacterial tetrahydrofolate synthesis. Indicated for urinary tract infections, acute otitis media, Shigella enteritis, Pneumocystis jirovecii pneumonia (PJP) treatment and prophylaxis, and community-acquired MRSA skin infections.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Trimethoprim.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Co-trimoxazole (Sulphamethoxazole 200mg + Trimethoprim 40mg per 5ml) Oral Suspension | 50 ml | ₹9.45 | BACTRIM, STANROX, HANPRIM, SEPTRAN | ₹13.35 | 29% Save |
| Co-trimoxazole (Sulphamethoxazole 800mg + Trimethoprim 160mg) Tablets | 10's | ₹11.34 | CO TRIMOXAZOLE, VIKTRIM, TRIMZOLE DS, SEPTRAN, LARPRIM DS | ₹20.84 | 46% Save |
| Co-trimoxazole (Sulphamethoxazole 100mg + Trimethoprim 20mg) Tablets | 10's | ₹2.06 | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
Get answers to common queries about Trimethoprim generics.