Thalidomide
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.
🧴 Clinical Application
Take orally once daily with water, preferably at bedtime at least 1 hour after dinner to mitigate profound sedative effects. Swallow capsules whole. Complete pregnancy testing prior to dispensing. Co-administer prophylactic anticoagulation.
⚠️ Side Effects
Common: Somnolence/sedation, profound constipation, dizziness, peripheral neuropathy (symmetric painful paresthesias, often irreversible), tremor, edema. Rare/Severe: Catastrophic phocomelia (amelia, phocomelia, internal organ defects), venous thromboembolism (DVT/PE), bradycardia, and Stevens-Johnson syndrome.
🛡️ Safety Warnings
Black Box Warning: Severe life-threatening teratogenicity / phocomelia; absolute contraindication in pregnancy; strict pregnancy prevention program and two forms of contraception required. Black Box Warning: Venous thromboembolism; mandatory anticoagulation. Causes irreversible peripheral neuropathy; monitor closely and discontinue at early signs of sensory loss.
Jan Aushadhi Products containing Thalidomide
Found 3 generic formulation(s) containing this active ingredient.
Thalidomide Capsules 100mg
Thalidomide Capsules (50mg, 100mg, 200mg) is the prototypical immunomodulatory drug (IMiD) on the WHO Model List of Essential Medicines. It binds to cereblon (CRBN), promoting degradation of IKZF1 and IKZF3, and suppresses tumor necrosis factor-alpha (TNF-alpha) synthesis while inhibiting basic fibroblast growth factor (bFGF) and VEGF-induced angiogenesis. Indicated in combination with dexamethasone for newly diagnosed multiple myeloma and for acute treatment and maintenance of erythema nodosum leprosum (ENL / Hansen's disease).
Thalidomide Capsules 200mg
Thalidomide Capsules (50mg, 100mg, 200mg) is the prototypical immunomodulatory drug (IMiD) on the WHO Model List of Essential Medicines. It binds to cereblon (CRBN), promoting degradation of IKZF1 and IKZF3, and suppresses tumor necrosis factor-alpha (TNF-alpha) synthesis while inhibiting basic fibroblast growth factor (bFGF) and VEGF-induced angiogenesis. Indicated in combination with dexamethasone for newly diagnosed multiple myeloma and for acute treatment and maintenance of erythema nodosum leprosum (ENL / Hansen's disease).
Thalidomide Capsules 50mg
Thalidomide Capsules (50mg, 100mg, 200mg) is the prototypical immunomodulatory drug (IMiD) on the WHO Model List of Essential Medicines. It binds to cereblon (CRBN), promoting degradation of IKZF1 and IKZF3, and suppresses tumor necrosis factor-alpha (TNF-alpha) synthesis while inhibiting basic fibroblast growth factor (bFGF) and VEGF-induced angiogenesis. Indicated in combination with dexamethasone for newly diagnosed multiple myeloma and for acute treatment and maintenance of erythema nodosum leprosum (ENL / Hansen's disease).
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Thalidomide.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Thalidomide Capsules 100mg | 10's | ₹165.00 | THALIX, THYCAD, THALODA, REDEMIDE, THALIMAX | ₹431.98 | 62% Save |
| Thalidomide Capsules 200mg | 10's | ₹234.38 | THALIDE, THALIX | ₹1164.00 | 80% Save |
| Thalidomide Capsules 50mg | 10's | ₹92.81 | THYCAD, REDEMIDE | ₹273.26 | 66% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Thalidomide generics.