⚕ Rx (Prescription Required)Oncology & Critical CareImmunosuppressants & Transplant Care

Sirolimus

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.

🧴 Clinical Application

Take orally once daily consistently with or without food, with a glass of water. Therapeutic Drug Monitoring (TDM) of whole blood trough levels (C0) is mandatory (target typically 4-12 ng/mL). Take 4 hours after cyclosporine.

⚠️ Side Effects

Common: Hypertriglyceridemia, hypercholesterolemia, peripheral edema, thrombocytopenia, leukopenia, stomatitis/mouth ulcers, impaired wound healing. Rare/Severe: Interstitial pneumonitis / pulmonary toxicity, proteinuria / focal segmental glomerulosclerosis, and hepatic artery thrombosis in liver transplant recipients.

🛡️ Safety Warnings

Black Box Warning: Increased mortality and graft loss in liver and lung transplant recipients; not recommended for liver or lung transplants. Black Box Warning: Impaired wound healing; do not initiate immediately post-surgery. Regularly monitor lipid panel, CBC, and trough blood levels. Non-nephrotoxic alternative to tacrolimus/cyclosporine.

Jan Aushadhi Products containing Sirolimus

Found 1 generic formulation(s) containing this active ingredient.

⚕ Rx OnlyImmunosuppressants & Transplant Care

Sirolimus Tablets 1mg

Tablets
10's

Sirolimus / Rapamycin Tablets (1mg) is a macrocyclic lactone immunosuppressive agent on the WHO Model List framework. It binds intracellularly to immunophilin FKBP-12, but unlike tacrolimus, the sirolimus-FKBP-12 complex binds to and inhibits the mammalian target of rapamycin (mTOR) kinase complex 1 (mTORC1). This blocks IL-2-stimulated progression from G1 to S phase in T-lymphocytes. Completely non-nephrotoxic compared to calcineurin inhibitors. Indicated for prophylaxis of organ rejection in kidney transplant recipients (often to spare calcineurin inhibitor nephrotoxicity) and treatment of lymphangioleiomyomatosis (LAM).

₹187.5₹1160.9484% saved
Sirolimus

Brand Equivalents & Price Comparison

Compare Jan Aushadhi generic prices against popular commercial brands for Sirolimus.

Generic FormulationPack SizeJan Aushadhi PriceCommercial Brand EquivalentsAvg. Commercial PriceSavings
Sirolimus Tablets 1mg10's₹187.50SIROMUS, RAPAREN₹1160.9484% Save

Frequently Asked Questions (FAQ)

Get answers to common queries about Sirolimus generics.

How many Jan Aushadhi products contain Sirolimus?＋
This directory currently lists 1 Jan Aushadhi generic product(s) containing Sirolimus as an active pharmaceutical ingredient (API). The count reflects the July 2026 PMBI catalog snapshot.
Does Sirolimus require a prescription at Jan Aushadhi Kendras?＋
Yes. Sirolimus is classified as a prescription-required (Rx) ingredient under applicable Indian drug schedules. You must present a valid prescription from a registered medical practitioner to obtain it at a Jan Aushadhi Kendra.
What is the lowest listed price for Sirolimus at Jan Aushadhi?＋
Based on the July 2026 PMBI catalog, the lowest listed MRP for a Sirolimus formulation is ₹187.50. Individual prices vary by pack size and dosage form. Use the product links above for the exact MRP of each formulation.
Are Jan Aushadhi Sirolimus products clinically equivalent to branded versions?＋
Jan Aushadhi generics contain the same declared active pharmaceutical ingredient (Sirolimus) at the same concentration as branded counterparts and must meet CDSCO quality standards. However, inactive excipients, release mechanisms, and manufacturing processes can differ between manufacturers. Never switch a prescribed medicine without consulting your doctor.
Find a Jan Aushadhi Kendra Near You
Search 21,118 listed government pharmacies across India by PIN code. Find Sirolimus products at government prices.
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