Phenytoin
Active pharmaceutical substance formulated in Jan Aushadhi generic products for CNS, Nerve & Mental Health treatment.
🧴 Clinical Application
Take orally with water, at the same times each day, with or immediately after food to reduce gastric irritation. Do not alter dose or switch formulations without therapeutic drug monitoring (target serum range: 10-20 mcg/mL). Maintain meticulous oral hygiene.
⚠️ Side Effects
Common: Nystagmus, ataxia, slurred speech, dizziness, gingival hyperplasia (gum swelling), hirsutism, coarsening of facial features. Rare/Severe: Boxed warning: Cardiovascular collapse and arrhythmias with rapid IV injection; cerebellar atrophy (with chronic high levels), DRESS syndrome, Stevens-Johnson syndrome, megaloblastic anemia, and osteomalacia.
🛡️ Safety Warnings
Boxed warning for rapid parenteral administration (hypotension and arrhythmias). Saturation pharmacokinetics requires routine therapeutic drug monitoring. Potent inducer of CYP3A4, CYP2C9, and CYP2C19. Mandatory oral hygiene and flossing to prevent severe gingival overgrowth.
Jan Aushadhi Products containing Phenytoin
Found 2 generic formulation(s) containing this active ingredient.
Phenytoin Tablets 100 mg
Phenytoin is a classic hydantoin antiepileptic on the WHO Model List of Essential Medicines. It voltage- and use-dependently promotes sodium channel inactivation, stabilizing neuronal membranes and limiting the spread of seizure activity from epileptic foci. Exhibits non-linear (Michaelis-Menten) saturation pharmacokinetics, where small dose increases can produce disproportionate, toxic rises in plasma concentrations. Indicated for tonic-clonic (grand mal) seizures, focal seizures, and prevention/treatment of seizures following neurosurgery.
Phenytoin Injection 100mg per 2 ml
Phenytoin is a classic hydantoin antiepileptic on the WHO Model List of Essential Medicines. It voltage- and use-dependently promotes sodium channel inactivation, stabilizing neuronal membranes and limiting the spread of seizure activity from epileptic foci. Exhibits non-linear (Michaelis-Menten) saturation pharmacokinetics, where small dose increases can produce disproportionate, toxic rises in plasma concentrations. Indicated for tonic-clonic (grand mal) seizures, focal seizures, and prevention/treatment of seizures following neurosurgery.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Phenytoin.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Phenytoin Tablets 100 mg | 100's in Bottle | ₹56.72 | EPTOIN, EPSOLIN, EPILAN, CELETOIN | ₹172.88 | 67% Save |
| Phenytoin Injection 100mg per 2 ml | 2ml Ampoule | ₹7.50 | EPTOIN | ₹24.40 | 69% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Phenytoin generics.