Pazopanib
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.
🧴 Clinical Application
Take orally 800 mg once daily on an EMPTY STOMACH: at least 1 hour before or 2 hours after food with a full glass of water. Swallow tablets whole; do NOT crush or chew, as crushing increases bioavailability and escalates systemic toxicity.
⚠️ Side Effects
Common: Hypertension, diarrhea, hair color depigmentation (hair lightening), nausea, anorexia, vomiting, fatigue, elevated transaminases. Rare/Severe: Severe fatal hepatotoxicity, arterial thromboembolic events, gastrointestinal perforation, and QT prolongation / Torsades de Pointes.
🛡️ Safety Warnings
Black Box Warning: Severe, fatal hepatotoxicity; monitor serum liver tests every 2 weeks for the first 9 weeks, then monthly. Must be taken on an empty stomach. Discontinue if baseline transaminases rise significantly or bilirubin exceeds 2× ULN.
Jan Aushadhi Products containing Pazopanib
Found 2 generic formulation(s) containing this active ingredient.
Pazopanib Tablets 200mg
Pazopanib Tablets (200mg, 400mg) is an oral second-generation multi-tyrosine kinase inhibitor on the WHO Model List framework. It potently inhibits VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-alpha, PDGFR-beta, and c-KIT, starving tumors of blood supply. Indicated for advanced renal cell carcinoma (RCC) and advanced soft tissue sarcoma (STS) in patients who have received prior chemotherapy.
Pazopanib Tablets 400mg
Pazopanib Tablets (200mg, 400mg) is an oral second-generation multi-tyrosine kinase inhibitor on the WHO Model List framework. It potently inhibits VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-alpha, PDGFR-beta, and c-KIT, starving tumors of blood supply. Indicated for advanced renal cell carcinoma (RCC) and advanced soft tissue sarcoma (STS) in patients who have received prior chemotherapy.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Pazopanib.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Pazopanib Tablets 200mg | 30's bottle in Monopack | ₹2062.50 | PAZINIB, PAZZVIDA, PAZEQOL, BDPAZO, BIOPANIB | ₹2156.89 | 4% Save |
| Pazopanib Tablets 400mg | 30's bottle in Monopack | ₹2906.25 | PAZONAT, PAZINIB, PAZZVIDA, PAZEQOL, BIOPANIB | ₹2617.90 | N/A |
Frequently Asked Questions (FAQ)
Get answers to common queries about Pazopanib generics.