Immunoglobulin

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Antibiotics & Anti-Infectives treatment.

🧴 Clinical Application

Administered strictly in specialized clinical or hospital settings. IV formulations are infused slowly starting at a low rate (e.g. 0.5-1 mL/kg/hr) and titrated gradually under continuous monitoring of vital signs. IM formulations are injected deep into large muscle masses.

⚠️ Side Effects

Common: Headache, chills, fever, flushing, nausea, backache, fatigue during infusion. Rare/Severe: Anaphylaxis (especially in IgA-deficient individuals), aseptic meningitis syndrome, acute renal failure (osmotic nephrosis associated with sucrose stabilizers), thrombosis/stroke, and transfusion-related acute lung injury (TRALI).

🛡️ Safety Warnings

Contraindicated in patients with selective IgA deficiency who possess anti-IgA antibodies (high risk of fatal anaphylaxis). Ensure adequate hydration before infusion. Monitor renal function and hydration, particularly in elderly or diabetic patients.