⚕ Rx (Prescription Required)Oncology & Critical CareCytotoxic Chemotherapy Formulations

Fluorouracil

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.

🧴 Clinical Application

Administer intravenously as an IV bolus or continuous IV infusion (often over 24 to 46 hours using an ambulatory infusion pump) as part of multi-agent chemotherapy regimens (FOLFOX, FOLFIRI, FLOT). Leucovorin is given prior to 5-FU to stabilize the TS-FdUMP inhibitory complex.

⚠️ Side Effects

Common: Mucositis/stomatitis, diarrhea, myelosuppression (neutropenia with bolus regimens), hand-foot syndrome (palmar-plantar erythrodysesthesia with continuous infusions), alopecia, nausea. Rare/Severe: Coronary vasospasm, myocardial ischemia/infarction, cerebellar ataxia, and lethal toxicity in patients with dihydropyrimidine dehydrogenase (DPD) deficiency.

🛡️ Safety Warnings

Black Box Warning: Patients with dihydropyrimidine dehydrogenase (DPD) deficiency cannot catabolize 5-FU and develop life-threatening pancytopenia, enteritis, and shock; pre-treatment DPD testing is strongly recommended. Cardiotoxicity warning (coronary vasospasm/angina); monitor cardiac status. Uridine triacetate is the specific antidote for overdose or severe early-onset toxicity.

Jan Aushadhi Products containing Fluorouracil

Found 1 generic formulation(s) containing this active ingredient.

⚕ Rx OnlyCytotoxic Chemotherapy Formulations

5-Flurouracil Injection 500mg

Injection
10 ml

5-Fluorouracil (5-FU) Injection (500mg) is a fluorinated pyrimidine antimetabolite on the WHO Model List of Essential Medicines. It is intracellularly converted to 5-fluoro-2'-deoxyuridine-5'-monophosphate (FdUMP), which forms a stable ternary complex with thymidylate synthase (TS) and 5,10-methylenetetrahydrofolate (potentiated by leucovorin), blocking thymidylate and DNA synthesis. Indicated for colorectal carcinoma, breast cancer, gastric cancer, pancreatic adenocarcinoma, and head and neck cancers.

₹11.5₹35.968% saved
Fluorouracil

Brand Equivalents & Price Comparison

Compare Jan Aushadhi generic prices against popular commercial brands for Fluorouracil.

Generic FormulationPack SizeJan Aushadhi PriceCommercial Brand EquivalentsAvg. Commercial PriceSavings
5-Flurouracil Injection 500mg10 ml₹11.50ONCOFLUOR, FLOCIL₹35.9068% Save

Frequently Asked Questions (FAQ)

Get answers to common queries about Fluorouracil generics.

How many Jan Aushadhi products contain Fluorouracil?＋
This directory currently lists 1 Jan Aushadhi generic product(s) containing Fluorouracil as an active pharmaceutical ingredient (API). The count reflects the July 2026 PMBI catalog snapshot.
Does Fluorouracil require a prescription at Jan Aushadhi Kendras?＋
Yes. Fluorouracil is classified as a prescription-required (Rx) ingredient under applicable Indian drug schedules. You must present a valid prescription from a registered medical practitioner to obtain it at a Jan Aushadhi Kendra.
What is the lowest listed price for Fluorouracil at Jan Aushadhi?＋
Based on the July 2026 PMBI catalog, the lowest listed MRP for a Fluorouracil formulation is ₹11.50. Individual prices vary by pack size and dosage form. Use the product links above for the exact MRP of each formulation.
Are Jan Aushadhi Fluorouracil products clinically equivalent to branded versions?＋
Jan Aushadhi generics contain the same declared active pharmaceutical ingredient (Fluorouracil) at the same concentration as branded counterparts and must meet CDSCO quality standards. However, inactive excipients, release mechanisms, and manufacturing processes can differ between manufacturers. Never switch a prescribed medicine without consulting your doctor.
Find a Jan Aushadhi Kendra Near You
Search 21,118 listed government pharmacies across India by PIN code. Find Fluorouracil products at government prices.
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