Erlotinib
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.
🧴 Clinical Application
Take orally once daily on an EMPTY STOMACH: at least 1 hour before or 2 hours after food with a full glass of water. Food dramatically increases bioavailability by nearly 100%, leading to severe toxicities. Avoid smoking (cigarette smoke induces CYP1A2, reducing erlotinib plasma levels by >50-60%).
⚠️ Side Effects
Common: Acneiform pustular skin rash (face, chest, back in >75% of patients; rash presence correlates with tumor response), diarrhea, anorexia, fatigue, paronychia, dry skin. Rare/Severe: Interstitial lung disease (ILD / pneumonitis), corneal perforation/ulceration, and gastrointestinal perforation.
🛡️ Safety Warnings
Must be taken on an empty stomach. Interrupt or discontinue immediately if acute onset of unexplained dyspnea, cough, and fever occurs (interstitial lung disease can be fatal). Concomitant use of PPIs (omeprazole, pantoprazole) decreases erlotinib absorption by >50%; space antacids or avoid PPIs. Dose must be increased in active cigarette smokers.
Jan Aushadhi Products containing Erlotinib
Found 1 generic formulation(s) containing this active ingredient.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Erlotinib.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Erlotinib Tablets 150 mg | 10's Bottle | ₹656.25 | ZYCEVA, ERLOT, ERLOTAD | ₹2182.42 | 70% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Erlotinib generics.