Deferiprone
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Vitamins, Minerals & Nutrition treatment.
🧴 Clinical Application
Take orally 25 mg/kg body weight three times daily (total 75 mg/kg/day, maximum 100 mg/kg/day) with water. Can be taken with meals to reduce nausea. Regular compliance is vital to prevent cardiac iron toxicity.
⚠️ Side Effects
Common: Chromaturia (reddish-brown discoloration of urine), nausea, vomiting, abdominal pain, arthralgia (joint pain), increased ALT. Rare/Severe: Severe agranulocytosis (can lead to fatal septic shock), neutropenia, and liver fibrosis.
🛡️ Safety Warnings
Black Box Warning: Agranulocytosis and neutropenia; monitor absolute neutrophil count (ANC) WEEKLY throughout therapy. Discontinue immediately if patient develops fever, sore throat, or symptoms of infection until ANC is confirmed. Do NOT take with aluminum-based antacids.
Jan Aushadhi Products containing Deferiprone
Found 2 generic formulation(s) containing this active ingredient.
Deferiprone Capsules 250mg
Deferiprone Capsules (250mg, 500mg) is an orally active bidentate iron chelator on the WHO Model List of Essential Medicines. It binds ferric iron (Fe3+) in a 3:1 ratio and easily crosses cell membranes, selectively removing intracellular iron from hepatocytes and cardiomyocytes (superior cardiac iron clearance compared to desferrioxamine). Chelation complexes are excreted predominantly in the urine. Indicated for treatment of transfusional iron overload in patients with thalassemia major when deferoxamine or deferasirox therapy is contraindicated or inadequate.
Deferiprone Capsules 500mg
Deferiprone Capsules (250mg, 500mg) is an orally active bidentate iron chelator on the WHO Model List of Essential Medicines. It binds ferric iron (Fe3+) in a 3:1 ratio and easily crosses cell membranes, selectively removing intracellular iron from hepatocytes and cardiomyocytes (superior cardiac iron clearance compared to desferrioxamine). Chelation complexes are excreted predominantly in the urine. Indicated for treatment of transfusional iron overload in patients with thalassemia major when deferoxamine or deferasirox therapy is contraindicated or inadequate.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Deferiprone.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Deferiprone Capsules 250mg | 50's | ₹137.16 | KELFER | ₹322.82 | 58% Save |
| Deferiprone Capsules 500mg | 50's | ₹257.81 | KELFER | ₹563.67 | 54% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Deferiprone generics.