⚕ Rx (Prescription Required)Oncology & Critical CareCytotoxic Chemotherapy Formulations

Dacarbazine

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.

🧴 Clinical Application

Administer intravenously by slow infusion over 15 to 30 minutes diluted in 5% Dextrose or 0.9% NaCl. Protect solution from light during administration. Administer antiemetics beforehand (highly emetogenic).

⚠️ Side Effects

Common: Severe acute nausea and vomiting (>90% of patients), bone marrow depression (leukopenia, thrombocytopenia nadir at 21-25 days), flu-like syndrome, alopecia, local burning/pain along the infusion vein. Rare/Severe: Hepatic vein thrombosis / hepatic necrosis (Budd-Chiari syndrome), anaphylaxis, and tissue necrosis upon extravasation.

🛡️ Safety Warnings

Black Box Warning: Severe bone marrow suppression and hepatic necrosis with vascular thrombosis (fatal Budd-Chiari syndrome). Highly emetogenic; pre-medicate aggressively. Extravasation causes severe pain and tissue damage. Protect infusion line from direct sunlight.

Jan Aushadhi Products containing Dacarbazine

Found 1 generic formulation(s) containing this active ingredient.

⚕ Rx OnlyCytotoxic Chemotherapy Formulations

Dacarbazine Injection 200mg

Injection
VIAL

Dacarbazine Injection (200mg) is an alkylating triazene antineoplastic on the WHO Model List of Essential Medicines. Following hepatic CYP1A bioactivation, it degrades to diazomethane and active 5-aminoimidazole-4-carboxamide (AIC), generating reactive methonium ions that alkylate DNA at O-6 and N-7 guanine positions. Indicated as a fundamental component of the ABVD regimen for Hodgkin lymphoma, metastatic malignant melanoma, and soft tissue sarcomas.

₹176.25
Dacarbazine

Brand Equivalents & Price Comparison

Compare Jan Aushadhi generic prices against popular commercial brands for Dacarbazine.

Generic FormulationPack SizeJan Aushadhi PriceCommercial Brand EquivalentsAvg. Commercial PriceSavings
Dacarbazine Injection 200mgVIAL₹176.25Dacarex, DABAZ₹172.67N/A

Frequently Asked Questions (FAQ)

Get answers to common queries about Dacarbazine generics.

How many Jan Aushadhi products contain Dacarbazine?＋
This directory currently lists 1 Jan Aushadhi generic product(s) containing Dacarbazine as an active pharmaceutical ingredient (API). The count reflects the July 2026 PMBI catalog snapshot.
Does Dacarbazine require a prescription at Jan Aushadhi Kendras?＋
Yes. Dacarbazine is classified as a prescription-required (Rx) ingredient under applicable Indian drug schedules. You must present a valid prescription from a registered medical practitioner to obtain it at a Jan Aushadhi Kendra.
What is the lowest listed price for Dacarbazine at Jan Aushadhi?＋
Based on the July 2026 PMBI catalog, the lowest listed MRP for a Dacarbazine formulation is ₹176.25. Individual prices vary by pack size and dosage form. Use the product links above for the exact MRP of each formulation.
Are Jan Aushadhi Dacarbazine products clinically equivalent to branded versions?＋
Jan Aushadhi generics contain the same declared active pharmaceutical ingredient (Dacarbazine) at the same concentration as branded counterparts and must meet CDSCO quality standards. However, inactive excipients, release mechanisms, and manufacturing processes can differ between manufacturers. Never switch a prescribed medicine without consulting your doctor.
Find a Jan Aushadhi Kendra Near You
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