Cyclobenzaprine

Aceclofenac (200mg sustained-release) and Cyclobenzaprine (15mg sustained-release) Tablets combines a long-acting NSAID with a tricyclic-derivative centrally acting muscle relaxant. Cyclobenzaprine acts primarily at the brainstem to reduce tonic somatic motor activity influencing both alpha and gamma motor systems. Indicated for acute, painful musculoskeletal conditions associated with muscle spasm and stiffness (e.g., severe acute low back pain).

Cyclobenzaprine Hydrochloride is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepressants. It acts primarily at the brainstem level to reduce tonic somatic motor activity through descending serotonergic and noradrenergic pathways, relieving acute voluntary muscle spasm without interfering with peripheral muscle function. Indicated for short-term relief of muscle spasm associated with acute, painful musculoskeletal conditions.