Clavulanicacid

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Antibiotics & Anti-Infectives treatment.

🧴 Clinical Application

For paediatric use. Reconstitute dry syrup with boiled, cooled water up to the graduation mark. Shake vigorously before each use. Administer at the start of a meal or with a light snack to maximize clavulanate absorption and minimize gastrointestinal irritation. Store in a refrigerator (2-8°C) and discard after 7 days.

⚠️ Side Effects

Common: Diarrhea, loose stools, nausea, vomiting, abdominal cramping, and cutaneous rashes. Rare/Severe: Severe anaphylaxis/angioedema, cholestatic jaundice/acute hepatitis, Stevens-Johnson syndrome, and Clostridioides difficile colitis.

🛡️ Safety Warnings

Absolute contraindication in patients with a history of severe penicillin or beta-lactam hypersensitivity, or amoxycillin/clavulanate-associated cholestatic jaundice or hepatic impairment. Discontinue immediately if rash or allergic wheezing develops. Adjust dosage in patients with significant renal impairment.