Cabergoline

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Women's Health & Hormones treatment.

🧴 Clinical Application

Take orally with food and water to minimize nausea and postural hypotension: For hyperprolactinemia: Initial dose is 0.25 mg to 0.5 mg once or twice weekly (e.g. Monday and Thursday); titrate monthly by 0.5 mg weekly increments based on serum prolactin levels (typical maintenance dose: 0.5 to 1 mg twice weekly). For lactation suppression: 1 mg as a single oral dose within 24 hours postpartum. Take with evening meal or bedtime.

⚠️ Side Effects

Common: Nausea, dizziness, orthostatic hypotension, headache, fatigue, drowsiness, constipation, abdominal pain, and depression. Rare/Severe: Cardiac valvulopathy, pulmonary/pleural/retroperitoneal fibrosis (associated with cumulative high doses), psychotic episodes, impulse control disorders (pathological gambling, hypersexuality), and angina.

🛡️ Safety Warnings

Contraindicated in uncontrolled hypertension, history of cardiac valvular disorders, history of pulmonary, pericardial, or retroperitoneal fibrotic disorders, and toxemia of pregnancy. Perform baseline echocardiogram prior to long-term therapy and every 6-12 months thereafter. Monitor blood pressure closely.