Brinzolamide
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Eye & Ear Care treatment.
🧴 Clinical Application
Shake suspension (brinzolamide) well before use. Instill one drop into the affected eye(s) two or three times daily. Perform nasolacrimal occlusion. Wait 10 minutes between different eye drops.
⚠️ Side Effects
Common: Bitter/sour taste in mouth (dysgeusia, via nasolacrimal drainage), burning, stinging, transient blurred vision, punctate keratitis. Rare/Severe: Sulfonamide hypersensitivity (angioedema, Stevens-Johnson syndrome), corneal decompensation, and aplastic anemia.
🛡️ Safety Warnings
Sulfonamide derivative: contraindicated in patients with known hypersensitivity to sulfonamides. Caution in patients with severe renal impairment (CrCl < 30 mL/min) or low endothelial cell counts (risk of irreversible corneal edema).
Jan Aushadhi Products containing Brinzolamide
Found 2 generic formulation(s) containing this active ingredient.
Brinzolamide Ophthalmic Suspension 1% w/v
Topical Carbonic Anhydrase Inhibitor (Dorzolamide 2% or Brinzolamide 1% suspension, alone or with Timolol) on the WHO Model List of Essential Medicines. It inhibits carbonic anhydrase II (CA-II) in the ciliary processes, slowing bicarbonate ion formation and reducing active sodium and fluid transport, thereby diminishing aqueous humor secretion by up to 20-30%. Indicated for intraocular pressure reduction in open-angle glaucoma and ocular hypertension.
Brinzolamide 10mg + Brimonidine 2mg Ophthalmic Suspension 5ml
Brimonidine Tartrate (0.1%, 0.2% w/v, alone or with Timolol/Brinzolamide) is a highly selective alpha-2 adrenergic receptor agonist on the WHO Model List of Essential Medicines. It exerts a dual mechanism: reducing aqueous humor production via alpha-2-mediated adenylyl cyclase inhibition in ciliary epithelium, and stimulating uveoscleral aqueous humor outflow via prostaglandin release. Also demonstrates retinal ganglion cell neuroprotective properties. Indicated for lowering intraocular pressure in open-angle glaucoma and ocular hypertension.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Brinzolamide.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Brinzolamide Ophthalmic Suspension 1% w/v | 5ml Drops | ₹37.50 | N/A | N/A | N/A |
| Brinzolamide 10mg + Brimonidine 2mg Ophthalmic Suspension 5ml | 5ml in Mono Carton | Under Process | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
Get answers to common queries about Brinzolamide generics.