Brimonidine
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Eye & Ear Care treatment.
🧴 Clinical Application
Instill one drop into the affected eye(s) once or twice daily. Apply gentle finger pressure to the inner corner of the eye (nasolacrimal occlusion) for 2 minutes immediately after instillation to minimize systemic cardiovascular and pulmonary absorption.
⚠️ Side Effects
Common: Transient eye burning, stinging, dry eyes, blurred vision. Rare/Severe: Systemic beta-blocker absorption: severe bradycardia, heart block, hypotension, syncope, bronchospasm, and exacerbation of congestive heart failure.
🛡️ Safety Warnings
Black box caution for systemic beta-blockade: Strictly contraindicated in bronchial asthma, severe COPD, sinus bradycardia, second- or third-degree AV block, and cardiogenic shock. Diabetic patients must be warned that timolol masks hypoglycemic tachycardia.
Jan Aushadhi Products containing Brimonidine
Found 3 generic formulation(s) containing this active ingredient.
Brimonidine Tartrate 0.2%w/v + Timolol Maleate 0.5%w/v Ophthalmic Solution
Timolol Maleate (0.5% w/v) is a non-selective beta-1 and beta-2 adrenergic receptor antagonist on the WHO Model List of Essential Medicines. It blocks beta-adrenergic receptors on non-pigmented ciliary epithelial cells, inhibiting cyclic AMP synthesis and reducing aqueous humor secretion by 30-50% without altering pupillary size or accommodation. Indicated for lowering elevated intraocular pressure in patients with chronic open-angle glaucoma and ocular hypertension.
Brimonidine Tartrate Eye drops 0.1% w/v
Brimonidine Tartrate (0.1%, 0.2% w/v, alone or with Timolol/Brinzolamide) is a highly selective alpha-2 adrenergic receptor agonist on the WHO Model List of Essential Medicines. It exerts a dual mechanism: reducing aqueous humor production via alpha-2-mediated adenylyl cyclase inhibition in ciliary epithelium, and stimulating uveoscleral aqueous humor outflow via prostaglandin release. Also demonstrates retinal ganglion cell neuroprotective properties. Indicated for lowering intraocular pressure in open-angle glaucoma and ocular hypertension.
Brinzolamide 10mg + Brimonidine 2mg Ophthalmic Suspension 5ml
Brimonidine Tartrate (0.1%, 0.2% w/v, alone or with Timolol/Brinzolamide) is a highly selective alpha-2 adrenergic receptor agonist on the WHO Model List of Essential Medicines. It exerts a dual mechanism: reducing aqueous humor production via alpha-2-mediated adenylyl cyclase inhibition in ciliary epithelium, and stimulating uveoscleral aqueous humor outflow via prostaglandin release. Also demonstrates retinal ganglion cell neuroprotective properties. Indicated for lowering intraocular pressure in open-angle glaucoma and ocular hypertension.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Brimonidine.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Brimonidine Tartrate 0.2%w/v + Timolol Maleate 0.5%w/v Ophthalmic Solution | 5 ml | ₹46.88 | N/A | N/A | N/A |
| Brimonidine Tartrate Eye drops 0.1% w/v | 5 ml | ₹18.75 | ALPHAGAN, BIDIN | ₹416.79 | 96% Save |
| Brinzolamide 10mg + Brimonidine 2mg Ophthalmic Suspension 5ml | 5ml in Mono Carton | Under Process | N/A | N/A | N/A |
Frequently Asked Questions (FAQ)
Get answers to common queries about Brimonidine generics.