⚕ Rx (Prescription Required)Oncology & Critical CareCytotoxic Chemotherapy Formulations

Bleomycin

Active pharmaceutical substance formulated in Jan Aushadhi generic products for Oncology & Critical Care treatment.

🧴 Clinical Application

Administer intravenously, intramuscularly, or subcutaneously (10 to 20 units/m² per dose) once or twice weekly. For IV use, infuse slowly over at least 10 minutes. Cumulative lifetime dose must strictly not exceed 400 units (or 250 units/m²) to prevent fatal pulmonary fibrosis. Premedicate lymphoma patients with paracetamol and antihistamines for test-dose anaphylactoid reactions.

⚠️ Side Effects

Common: Hyperpigmentation of skin, flagellate erythema, hyperkeratosis, alopecia, stomatitis, fevers and chills within hours of infusion. Rare/Severe: Irreversible dose-dependent pulmonary fibrosis / pneumonitis, and fatal idiosyncratic anaphylactoid reactions in lymphoma patients.

🛡️ Safety Warnings

Black Box Warning: Dose-dependent pulmonary toxicity (interstitial pneumonitis progressing to fatal pulmonary fibrosis); monitor chest X-rays, DLCO, and pulmonary function tests regularly. Discontinue immediately if rales, dyspnea, or DLCO declines by >30-35%. High inspired oxygen fractions (FiO2 > 30% during anesthesia) can trigger lethal pulmonary toxicity. Minimal myelosuppression.

Jan Aushadhi Products containing Bleomycin

Found 1 generic formulation(s) containing this active ingredient.

⚕ Rx OnlyCytotoxic Chemotherapy Formulations

Bleomycin Injection 15 IU

Injection
Vial

Bleomycin Injection (15 IU) is a cytotoxic glycopeptide antibiotic on the WHO Model List of Essential Medicines. It binds to intracellular ferrous iron (Fe2+) and molecular oxygen to form an activated pseudoperoxidase complex that cleaves single- and double-stranded DNA via free radical generation, arresting cells primarily in the G2 and M phases. Unlike most antineoplastics, it causes virtually no bone marrow suppression. Indicated for curative combination chemotherapy of testicular carcinoma (BEP regimen), Hodgkin lymphoma (ABVD regimen), non-Hodgkin lymphoma, and squamous cell carcinomas of the cervix and head and neck.

Brand Equivalents & Price Comparison

Compare Jan Aushadhi generic prices against popular commercial brands for Bleomycin.

Generic FormulationPack SizeJan Aushadhi PriceCommercial Brand EquivalentsAvg. Commercial PriceSavings
Bleomycin Injection 15 IUVial₹300.00N/AN/AN/A

Frequently Asked Questions (FAQ)

Get answers to common queries about Bleomycin generics.

How many Jan Aushadhi products contain Bleomycin?+
This directory currently lists 1 Jan Aushadhi generic product(s) containing Bleomycin as an active pharmaceutical ingredient (API). The count reflects the July 2026 PMBI catalog snapshot.
Does Bleomycin require a prescription at Jan Aushadhi Kendras?+
Yes. Bleomycin is classified as a prescription-required (Rx) ingredient under applicable Indian drug schedules. You must present a valid prescription from a registered medical practitioner to obtain it at a Jan Aushadhi Kendra.
What is the lowest listed price for Bleomycin at Jan Aushadhi?+
Price data for Bleomycin formulations is currently listed as "under process" in the July 2026 PMBI catalog. Visit a Jan Aushadhi Kendra and quote the product drug code for the applicable MRP.
Are Jan Aushadhi Bleomycin products clinically equivalent to branded versions?+
Jan Aushadhi generics contain the same declared active pharmaceutical ingredient (Bleomycin) at the same concentration as branded counterparts and must meet CDSCO quality standards. However, inactive excipients, release mechanisms, and manufacturing processes can differ between manufacturers. Never switch a prescribed medicine without consulting your doctor.
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