Apixaban
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Cardiac & Hypertension treatment.
🧴 Clinical Application
Take orally twice daily (every 12 hours) with a glass of water, with or without food. Do not skip doses due to short half-life. Specific reversal agent (andexanet alfa) exists for life-threatening bleeds.
⚠️ Side Effects
Common: Minor bleeding, contusion, hematuria, epistaxis, anemia. Rare/Severe: Boxed warnings: Premature discontinuation increases the risk of thrombotic events; spinal/epidural hematoma in neuraxial anesthesia resulting in permanent paralysis; major fatal hemorrhage.
🛡️ Safety Warnings
Black box warnings: (1) Premature discontinuation increases the risk of stroke; (2) Spinal/epidural hematoma risk with lumbar puncture or epidural anesthesia. Contraindicated in active pathological bleeding and severe hepatic impairment. Dose reduction criteria (2.5 mg BID) apply if at least two of: age >= 80 years, weight <= 60 kg, or serum creatinine >= 1.5 mg/dL.
Jan Aushadhi Products containing Apixaban
Found 2 generic formulation(s) containing this active ingredient.
Apixaban Tablets 2.5mg
Apixaban is an oral, highly selective, reversible direct factor Xa inhibitor (DOAC) on the WHO Model List of Essential Medicines. It inhibits free and clot-bound factor Xa as well as prothrombinase activity, directly decreasing thrombin generation and thrombus development without requiring antithrombin III. Does not require routine INR monitoring. Indicated for stroke prevention in non-valvular atrial fibrillation, treatment and secondary prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE), and DVT prophylaxis following hip or knee arthroplasty.
Apixaban Tablets 5mg
Apixaban is an oral, highly selective, reversible direct factor Xa inhibitor (DOAC) on the WHO Model List of Essential Medicines. It inhibits free and clot-bound factor Xa as well as prothrombinase activity, directly decreasing thrombin generation and thrombus development without requiring antithrombin III. Does not require routine INR monitoring. Indicated for stroke prevention in non-valvular atrial fibrillation, treatment and secondary prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE), and DVT prophylaxis following hip or knee arthroplasty.
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Apixaban.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Apixaban Tablets 2.5mg | 10's | ₹18.75 | ELIQUIS, APIGAT, APIXATOR, APIGY, APIXAPIL | ₹219.89 | 91% Save |
| Apixaban Tablets 5mg | 10's | ₹32.81 | ELIQUIS, APIXATOR, APIGAT, APIGY, APIXAPIL | ₹217.16 | 85% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Apixaban generics.