Amiodarone
Active pharmaceutical substance formulated in Jan Aushadhi generic products for Cardiac & Hypertension treatment.
🧴 Clinical Application
Take orally with meals with water to decrease gastrointestinal upset. Swallow whole. Avoid grapefruit and grapefruit juice, which drastically increases amiodarone levels. Strict adherence to loading and maintenance dosing schedules directed by your electrophysiologist.
⚠️ Side Effects
Common: Corneal microdeposits (asymptomatic), photosensitivity (sunburn, slate-blue skin discoloration), nausea, constipation, tremor, ataxia. Rare/Severe: Boxed warnings: Fatal pulmonary toxicity (interstitial pneumonitis/alveolitis), severe hepatotoxicity, exacerbation of fatal arrhythmias; thyroid dysfunction (hypo- or hyperthyroidism due to iodine content), and optic neuropathy.
🛡️ Safety Warnings
Black box warnings: Fatal pulmonary toxicity, severe hepatotoxicity, and proarrhythmic effects. Baseline and periodic chest X-ray/PFTs, liver function tests, thyroid panels (TSH, T3, T4), and ECG (QTc) are mandatory. Avoid sun exposure and use high-SPF sunscreen. Interacts strongly with warfarin (doubles INR) and digoxin (doubles digoxin level).
Jan Aushadhi Products containing Amiodarone
Found 2 generic formulation(s) containing this active ingredient.
Amiodarone Tablets 200 mg
Amiodarone Hydrochloride is a broad-spectrum Class III antiarrhythmic agent on the WHO Model List of Essential Medicines. It predominantly blocks voltage-gated potassium channels, prolonging myocardial action potential duration and effective refractory period across all cardiac tissues, while also exhibiting Class I (sodium channel block), Class II (antiadrenergic non-competitive beta-block), and Class IV (calcium channel block) actions. Features an enormous volume of distribution and an elimination half-life of 40 to 60 days. Indicated for life-threatening ventricular arrhythmias (ventricular tachycardia, ventricular fibrillation) and supraventricular arrhythmias (atrial fibrillation/flutter).
Amiodarone Tablets 100 mg
Amiodarone Hydrochloride is a broad-spectrum Class III antiarrhythmic agent on the WHO Model List of Essential Medicines. It predominantly blocks voltage-gated potassium channels, prolonging myocardial action potential duration and effective refractory period across all cardiac tissues, while also exhibiting Class I (sodium channel block), Class II (antiadrenergic non-competitive beta-block), and Class IV (calcium channel block) actions. Features an enormous volume of distribution and an elimination half-life of 40 to 60 days. Indicated for life-threatening ventricular arrhythmias (ventricular tachycardia, ventricular fibrillation) and supraventricular arrhythmias (atrial fibrillation/flutter).
Brand Equivalents & Price Comparison
Compare Jan Aushadhi generic prices against popular commercial brands for Amiodarone.
| Generic Formulation | Pack Size | Jan Aushadhi Price | Commercial Brand Equivalents | Avg. Commercial Price | Savings |
|---|---|---|---|---|---|
| Amiodarone Tablets 200 mg | 10's | ₹60.84 | CORDARONE, TACHYRA | ₹115.33 | 47% Save |
| Amiodarone Tablets 100 mg | 10's | ₹31.97 | CORDARONE, TACHYRA | ₹60.75 | 47% Save |
Frequently Asked Questions (FAQ)
Get answers to common queries about Amiodarone generics.